I have a 400ex and have a twist throttle in it, but it doesnt give me too much fatigue in my arm. I bought a 250R with a twist throttle and i have to pull it three times more than the 400's to rev the maximun. I have big carbs on both. Is there anyway i could by another twist with less pulling or do i have to change to the thumb throttle in other to get less fatigue?

 

Try purchasing a 1/4 twist throttle for the 250R. Magura, Motion Pro, and Gunnar-Gasser all make them, with my preference in order as listed.